From I-75 From The South (Southwest Florida International Airport, Bonita Springs, Naples, and beyond) Take exit #138 and go west (left turn) on State Road 82. After approximately 4.5 miles, at the intersection with US 41, continue ahead onto State Road 867 (McGregor Boulevard). Travel approximately a mile and turn left on Hendry Street, First Street will be your first stop sign and bring you to the heart of downtown Fort Myers. From The North (Sarasota, Tampa and beyond) Take exit #158 (Tucker’s Grade) and go west (right turn) to US 41. At the US 41 junction (first traffic light), turn south (left). Continue on US 41 south through North Fort Myers. Cross the Caloosahatchee River Bridge and stay in the right lane. Take the first exit ramp for the Historic District, this will lead you to the heart of downtown. From State Road 82 - Martin Luther King Jr. Blvd. Travel west on State Road 82 (Martin Luther King Jr. Boulevard) and turn right on Hendry Street, this will lead you to First Street and the heart of downtown Ft. Myers. From US 41 From The South Heading north on US 41, head west (left turn) at Colonial Boulevard (State Road 884 West). Continue in the right lane. Follow the signs to McGregor Boulevard. Turn right onto McGregor Boulevard (last exit before the toll bridge to Cape Coral). At approximately 3 miles, turn left on Hendry Street, head towards First Street, this will lead you to the heart of downtown. From The North Heading South on US 41, cross the Caloosahatchee River Bridge and stay in the right lane. Follow the signs for Highway 867. Take the ramp for Historic District. This will lead you to the heart of downtown. From Highway 80 – Palm Beach Blvd. Travel west on Route 80 (Palm Beach Boulevard) into downtown Fort Myers. When the street becomes a one-way street, the name changes to First Street. Follow First Street and take a right onto Hendry Street. This will lead you to the heart of downtown. From Sanibel Captiva Islands Exiting Sanibel Island, continue approximately 2 miles past the toll booth on highway 869 (Summerlin Road). Turn north (left) on McGregor Boulevard. Travel approximately 13 miles on McGregor Boulevard (Highway 867). Turn left on Hendry Street and follow down to First Street. This will lead you to the heart of downtown.